Counties with highest COVID-19 infection rates in Kentucky

Published 12:24 pm Thursday, March 17, 2022

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Counties with highest COVID-19 infection rates in Kentucky

The vaccine deployment in December 2020 signaled a turning point in the COVID-19 pandemic. By the end of May 2021, 40% of the U.S. population was fully vaccinated. But as vaccination rates lagged over the summer, new surges of COVID-19 came, including Delta in the summer of 2021, and now the Omicron variant, which comprises the majority of cases in the U.S.

Researchers around the world have reported that Omicron is more transmissible than Delta, making breakthrough and repeat infections more likely. Early research suggests this strain may cause less severe illness than Delta and the original virus, however, health officials have warned an Omicron-driven surge could still increase hospitalization and death rates—especially in areas with less vaccinated populations.

The United States as of March 16 reached 967,175 COVID-19-related deaths and 79.6 million COVID-19 cases, according to Johns Hopkins University. Currently, 65.3% of the population is fully vaccinated, and 44.4% have received booster doses.

Stacker compiled a list of the counties with highest COVID-19 infection rates in Kentucky using data from the U.S. Department of Health & Human Services and vaccination data from Covid Act Now. Counties are ranked by the highest infection rate per 100,000 residents within the week leading up to March 15, 2021. Cumulative cases per 100,000 served as a tiebreaker.

Keep reading to see whether your county ranks among the highest COVID-19 infection rates in your state.

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#50. Boone County, KY

– New cases per 100k in the past week: 209 (279 new cases, -6% change from previous week)
– Cumulative cases per 100k: 27,414 (36,620 total cases)
— 5.7% less cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 204 (272 total deaths)
— 36.6% less deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 61.7% (82,450 fully vaccinated)

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#49. Christian County, KY

– New cases per 100k in the past week: 211 (149 new cases, -50% change from previous week)
– Cumulative cases per 100k: 23,000 (16,206 total cases)
— 20.9% less cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 282 (199 total deaths)
— 12.4% less deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 35.8% (25,198 fully vaccinated)

Brian Stansberry // Wikimedia Commons

#48. Harrison County, KY

– New cases per 100k in the past week: 222 (42 new cases, -18% change from previous week)
– Cumulative cases per 100k: 32,649 (6,166 total cases)
— 12.3% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 339 (64 total deaths)
— 5.3% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 49.8% (9,400 fully vaccinated)

W.marsh // Wikimedia Commons

#47. Harlan County, KY

– New cases per 100k in the past week: 223 (58 new cases, -40% change from previous week)
– Cumulative cases per 100k: 35,213 (9,159 total cases)
— 21.1% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 727 (189 total deaths)
— 125.8% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 46.0% (11,964 fully vaccinated)

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#46. Lincoln County, KY

– New cases per 100k in the past week: 224 (55 new cases, +15% change from previous week)
– Cumulative cases per 100k: 25,541 (6,270 total cases)
— 12.1% less cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 509 (125 total deaths)
— 58.1% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 40.6% (9,958 fully vaccinated)

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#45. Cumberland County, KY

– New cases per 100k in the past week: 227 (15 new cases, -52% change from previous week)
– Cumulative cases per 100k: 32,794 (2,169 total cases)
— 12.8% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 423 (28 total deaths)
— 31.4% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 44.3% (2,929 fully vaccinated)

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#44. Lawrence County, KY

– New cases per 100k in the past week: 229 (35 new cases, -33% change from previous week)
– Cumulative cases per 100k: 29,510 (4,520 total cases)
— 1.5% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 411 (63 total deaths)
— 27.6% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 48.0% (7,354 fully vaccinated)

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#43. Fleming County, KY

– New cases per 100k in the past week: 233 (34 new cases, +3% change from previous week)
– Cumulative cases per 100k: 25,314 (3,691 total cases)
— 12.9% less cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 343 (50 total deaths)
— 6.5% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 51.2% (7,462 fully vaccinated)

JERRYE & ROY KLOTZ MD // Wikimedia Commons

#42. Franklin County, KY

– New cases per 100k in the past week: 237 (121 new cases, -19% change from previous week)
– Cumulative cases per 100k: 26,183 (13,351 total cases)
— 9.9% less cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 271 (138 total deaths)
— 15.8% less deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 60.8% (31,008 fully vaccinated)

CoryClaxon // Wikimedia Commons

#41. Carter County, KY

– New cases per 100k in the past week: 239 (64 new cases, -30% change from previous week)
– Cumulative cases per 100k: 31,854 (8,536 total cases)
— 9.6% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 369 (99 total deaths)
— 14.6% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 48.8% (13,081 fully vaccinated)

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#40. Bath County, KY

– New cases per 100k in the past week: 256 (32 new cases, -64% change from previous week)
– Cumulative cases per 100k: 23,640 (2,955 total cases)
— 18.7% less cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 312 (39 total deaths)
— 3.1% less deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 53.6% (6,700 fully vaccinated)

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#39. Floyd County, KY

– New cases per 100k in the past week: 261 (93 new cases, -33% change from previous week)
– Cumulative cases per 100k: 34,882 (12,414 total cases)
— 20.0% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 452 (161 total deaths)
— 40.4% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 56.7% (20,177 fully vaccinated)

JERRYE & ROY KLOTZ MD // Wikimedia Commons

#38. Owsley County, KY

– New cases per 100k in the past week: 272 (12 new cases, -25% change from previous week)
– Cumulative cases per 100k: 35,425 (1,564 total cases)
— 21.9% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 521 (23 total deaths)
— 61.8% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 47.2% (2,083 fully vaccinated)

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#37. Lyon County, KY

– New cases per 100k in the past week: 280 (23 new cases, -34% change from previous week)
– Cumulative cases per 100k: 34,653 (2,845 total cases)
— 19.2% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 402 (33 total deaths)
— 24.8% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 58.1% (4,766 fully vaccinated)

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#36. Clay County, KY

– New cases per 100k in the past week: 281 (56 new cases, -8% change from previous week)
– Cumulative cases per 100k: 39,249 (7,811 total cases)
— 35.0% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 427 (85 total deaths)
— 32.6% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 44.1% (8,769 fully vaccinated)

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#35. Hopkins County, KY

– New cases per 100k in the past week: 282 (126 new cases, -21% change from previous week)
– Cumulative cases per 100k: 33,221 (14,845 total cases)
— 14.3% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 553 (247 total deaths)
— 71.7% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 51.3% (22,927 fully vaccinated)

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#34. Martin County, KY

– New cases per 100k in the past week: 295 (33 new cases, -13% change from previous week)
– Cumulative cases per 100k: 29,227 (3,272 total cases)
— 0.6% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 438 (49 total deaths)
— 36.0% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 53.8% (6,022 fully vaccinated)

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#33. Grant County, KY

– New cases per 100k in the past week: 323 (81 new cases, +3% change from previous week)
– Cumulative cases per 100k: 27,341 (6,854 total cases)
— 5.9% less cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 215 (54 total deaths)
— 33.2% less deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 48.6% (12,171 fully vaccinated)

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#32. Whitley County, KY

– New cases per 100k in the past week: 328 (119 new cases, -43% change from previous week)
– Cumulative cases per 100k: 38,824 (14,079 total cases)
— 33.6% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 474 (172 total deaths)
— 47.2% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 43.9% (15,923 fully vaccinated)

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#31. Mason County, KY

– New cases per 100k in the past week: 334 (57 new cases, +27% change from previous week)
– Cumulative cases per 100k: 27,088 (4,624 total cases)
— 6.8% less cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 586 (100 total deaths)
— 82.0% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 50.5% (8,625 fully vaccinated)

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#30. Casey County, KY

– New cases per 100k in the past week: 347 (56 new cases, +27% change from previous week)
– Cumulative cases per 100k: 24,847 (4,015 total cases)
— 14.5% less cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 427 (69 total deaths)
— 32.6% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 35.8% (5,786 fully vaccinated)

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#29. Leslie County, KY

– New cases per 100k in the past week: 364 (36 new cases, -55% change from previous week)
– Cumulative cases per 100k: 37,258 (3,680 total cases)
— 28.2% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 395 (39 total deaths)
— 22.7% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 51.7% (5,102 fully vaccinated)

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#28. Clinton County, KY

– New cases per 100k in the past week: 382 (39 new cases, -44% change from previous week)
– Cumulative cases per 100k: 33,695 (3,443 total cases)
— 15.9% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 431 (44 total deaths)
— 33.9% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 40.3% (4,121 fully vaccinated)

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#27. Scott County, KY

– New cases per 100k in the past week: 391 (223 new cases, +23% change from previous week)
– Cumulative cases per 100k: 28,202 (16,076 total cases)
— 3.0% less cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 167 (95 total deaths)
— 48.1% less deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 55.3% (31,501 fully vaccinated)

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#26. Knott County, KY

– New cases per 100k in the past week: 392 (58 new cases, -15% change from previous week)
– Cumulative cases per 100k: 27,786 (4,114 total cases)
— 4.4% less cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 398 (59 total deaths)
— 23.6% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 47.5% (7,036 fully vaccinated)

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#25. Russell County, KY

– New cases per 100k in the past week: 396 (71 new cases, -10% change from previous week)
– Cumulative cases per 100k: 34,938 (6,262 total cases)
— 20.2% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 469 (84 total deaths)
— 45.7% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 45.5% (8,158 fully vaccinated)

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#24. Nicholas County, KY

– New cases per 100k in the past week: 399 (29 new cases, +93% change from previous week)
– Cumulative cases per 100k: 26,262 (1,909 total cases)
— 9.7% less cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 426 (31 total deaths)
— 32.3% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 52.8% (3,838 fully vaccinated)

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#23. Montgomery County, KY

– New cases per 100k in the past week: 412 (116 new cases, -26% change from previous week)
– Cumulative cases per 100k: 24,292 (6,840 total cases)
— 16.4% less cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 316 (89 total deaths)
— 1.9% less deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 46.1% (12,993 fully vaccinated)

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#22. Breathitt County, KY

– New cases per 100k in the past week: 428 (54 new cases, -24% change from previous week)
– Cumulative cases per 100k: 28,789 (3,636 total cases)
— 1.0% less cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 404 (51 total deaths)
— 25.5% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 52.3% (6,610 fully vaccinated)

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#21. Taylor County, KY

– New cases per 100k in the past week: 431 (111 new cases, -48% change from previous week)
– Cumulative cases per 100k: 34,937 (9,003 total cases)
— 20.2% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 450 (116 total deaths)
— 39.8% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 47.7% (12,280 fully vaccinated)

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#20. Pike County, KY

– New cases per 100k in the past week: 454 (263 new cases, -63% change from previous week)
– Cumulative cases per 100k: 32,321 (18,706 total cases)
— 11.2% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 456 (264 total deaths)
— 41.6% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 52.6% (30,416 fully vaccinated)

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#19. Clark County, KY

– New cases per 100k in the past week: 472 (171 new cases, +10% change from previous week)
– Cumulative cases per 100k: 27,932 (10,129 total cases)
— 3.9% less cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 154 (56 total deaths)
— 52.2% less deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 54.1% (19,634 fully vaccinated)

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#18. Magoffin County, KY

– New cases per 100k in the past week: 485 (59 new cases, +16% change from previous week)
– Cumulative cases per 100k: 31,864 (3,875 total cases)
— 9.6% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 345 (42 total deaths)
— 7.1% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 50.9% (6,187 fully vaccinated)

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#17. Anderson County, KY

– New cases per 100k in the past week: 506 (115 new cases, +14% change from previous week)
– Cumulative cases per 100k: 27,938 (6,355 total cases)
— 3.9% less cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 290 (66 total deaths)
— 9.9% less deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 54.8% (12,475 fully vaccinated)

C. Bedford Crenshaw // Wikimedia Commons

#16. Caldwell County, KY

– New cases per 100k in the past week: 518 (66 new cases, +8% change from previous week)
– Cumulative cases per 100k: 32,015 (4,081 total cases)
— 10.1% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 463 (59 total deaths)
— 43.8% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 51.8% (6,606 fully vaccinated)

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#15. Livingston County, KY

– New cases per 100k in the past week: 522 (48 new cases, -11% change from previous week)
– Cumulative cases per 100k: 25,941 (2,385 total cases)
— 10.8% less cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 642 (59 total deaths)
— 99.4% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 49.0% (4,506 fully vaccinated)

W.marsh // Wikimedia Commons

#14. Adair County, KY

– New cases per 100k in the past week: 526 (101 new cases, -19% change from previous week)
– Cumulative cases per 100k: 29,544 (5,673 total cases)
— 1.6% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 526 (101 total deaths)
— 63.4% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 39.0% (7,492 fully vaccinated)

W.marsh // Wikimedia Commons

#13. Laurel County, KY

– New cases per 100k in the past week: 526 (320 new cases, +41% change from previous week)
– Cumulative cases per 100k: 30,860 (18,767 total cases)
— 6.2% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 344 (209 total deaths)
— 6.8% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 40.2% (24,447 fully vaccinated)

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#12. Perry County, KY

– New cases per 100k in the past week: 536 (138 new cases, -41% change from previous week)
– Cumulative cases per 100k: 41,622 (10,721 total cases)
— 43.2% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 582 (150 total deaths)
— 80.7% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 61.7% (15,890 fully vaccinated)

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#11. Green County, KY

– New cases per 100k in the past week: 567 (62 new cases, -11% change from previous week)
– Cumulative cases per 100k: 32,922 (3,602 total cases)
— 13.3% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 356 (39 total deaths)
— 10.6% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 43.4% (4,748 fully vaccinated)

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#10. Menifee County, KY

– New cases per 100k in the past week: 601 (39 new cases, -17% change from previous week)
– Cumulative cases per 100k: 23,979 (1,556 total cases)
— 17.5% less cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 478 (31 total deaths)
— 48.4% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 44.2% (2,865 fully vaccinated)

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#9. Letcher County, KY

– New cases per 100k in the past week: 603 (130 new cases, +78% change from previous week)
– Cumulative cases per 100k: 32,019 (6,901 total cases)
— 10.2% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 459 (99 total deaths)
— 42.5% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 52.9% (11,393 fully vaccinated)

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#8. Wolfe County, KY

– New cases per 100k in the past week: 755 (54 new cases, -11% change from previous week)
– Cumulative cases per 100k: 34,400 (2,462 total cases)
— 18.3% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 265 (19 total deaths)
— 17.7% less deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 53.4% (3,822 fully vaccinated)

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#7. Crittenden County, KY

– New cases per 100k in the past week: 829 (73 new cases, -39% change from previous week)
– Cumulative cases per 100k: 25,437 (2,240 total cases)
— 12.5% less cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 522 (46 total deaths)
— 62.1% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 40.8% (3,594 fully vaccinated)

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#6. Elliott County, KY

– New cases per 100k in the past week: 905 (68 new cases, +62% change from previous week)
– Cumulative cases per 100k: 30,890 (2,322 total cases)
— 6.3% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 226 (17 total deaths)
— 29.8% less deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 35.4% (2,661 fully vaccinated)

JERRYE & ROY KLOTZ MD // Wikimedia Commons

#5. Wayne County, KY

– New cases per 100k in the past week: 964 (196 new cases, +13% change from previous week)
– Cumulative cases per 100k: 26,676 (5,424 total cases)
— 8.2% less cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 433 (88 total deaths)
— 34.5% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 41.6% (8,451 fully vaccinated)

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#4. Morgan County, KY

– New cases per 100k in the past week: 1,067 (142 new cases, +27% change from previous week)
– Cumulative cases per 100k: 36,321 (4,834 total cases)
— 25.0% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 158 (21 total deaths)
— 50.9% less deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 47.8% (6,368 fully vaccinated)

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#3. Trigg County, KY

– New cases per 100k in the past week: 1,222 (179 new cases, +29% change from previous week)
– Cumulative cases per 100k: 26,189 (3,837 total cases)
— 9.9% less cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 280 (41 total deaths)
— 13.0% less deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 46.6% (6,829 fully vaccinated)

Kybluegrass // Wikimedia Commons

#2. McCreary County, KY

– New cases per 100k in the past week: 1,248 (215 new cases, +21% change from previous week)
– Cumulative cases per 100k: 31,467 (5,422 total cases)
— 8.3% more cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 435 (75 total deaths)
— 35.1% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 38.9% (6,706 fully vaccinated)

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#1. Pulaski County, KY

– New cases per 100k in the past week: 1,260 (819 new cases, +94% change from previous week)
– Cumulative cases per 100k: 26,019 (16,907 total cases)
— 10.5% less cases per 100k residents than Kentucky
– Cumulative deaths per 100k: 406 (264 total deaths)
— 26.1% more deaths per 100k residents than Kentucky
– Population that is fully vaccinated: 45.8% (29,787 fully vaccinated)